A suspense novel crossed with a literary exploration of infidelity and marital rancor, Elizabeth Brundage's ambitious debut, The Doctor's Wife, provides more than the usual kick of adrenalin for readers. In a small town in upstate New York, urban transplants Annie and Michael Knowles--he is a rising OB/GYN, and she is a once-trailblazing journalist who has settled into a teaching job--hope to escape the noise and bustle of the city. But both are drawn into danger: Annie begins an affair with an infamous (and married) painter, Simon Haas, and Michael is coaxed into helping an ex-lover at her family planning clinic. He performs abortions for poor women, and tries to ignore the cars that follow him home and the increasingly threatening phone calls. ometimes Brundage perfectly navigates the twisting, overlapping elements of her complicated story line, but other times gives us too much at a time. And one of her characters, Simon's disturbed wife Lydia Haas, is so fascinating that she puts the others in the shade. Nevertheless, this is a rich first novel and a promising beginning for its author. --Regina Marler